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Isocarboxazid Antidepressant : Marplan

Brand Name : Marplan

ISOCARBOXAZID (Marplan®) belongs to a class of drugs called monoamine oxidase inhibitors (MAOIs). Isocarboxazid increases the level of certain chemicals in the brain that help fight depression and other mood problems, including certain anxiety disorders. Isocarboxazid can interact with certain foods and other medicines to cause unpleasant side effects. You must know what foods and medicines to avoid (see below). Generic isocarboxazid tablets are not yet available.

Uses of Isocarboxazid

• Marplan (isocarboxazid), is a medication that is used to treat depression.
• Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders.
• Usually, this medication is used in persons who have not responded to treatment with other drugs.
• This medication treats depression by restoring the balance of certain natural substances (neurotransmitters) in the brain.

How to Take Isocarboxazid

Take this medicine as directed. It can be taken with or without food. Do not stop taking this medicine abruptly without consulting with your doctor.

What are the Side Effects of Isocarboxazid Medication

Dizziness, drowsiness, tiredness, weakness, problems sleeping, constipation, and dry mouth may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Warnings and precautions before taking Isocarboxazid Medication

• This medicine may reduce the ability to drive or operate machinery safely.
• Avoid high protein food that has undergone breakdown by ageing, fermentation, pickling, smoking or bacterial contamination. (See the interactions section for further information).
• This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain kind of adrenal gland tumor (pheochromocytoma), cerebrovascular disease (e.g., stroke), heart problems (e.g., congestive heart failure, heart attack), high blood pressure, history of severe/frequent headaches, liver problems.
• To minimize dizziness and the risk of fainting, get up slowly when rising from a sitting or lying position.
• Do not eat or drink large amounts of caffeine-containing food or beverages such as coffee, tea, cola, or chocolate.

What drugs may interact with Isocarboxazid Tablet

Do not take acetaminophen/ butalbital/ caffeine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result.

What to do if you take Overdose of Isocarboxazid ?

Major overdosage may be evidenced by tachycardia, hypotension, coma, convulsions, respiratory depression, sluggish reflexes, pyrexia, and diaphoresis Symptoms of overdose include:

• Anxiety (severe)
• confusion
• convulsions (seizures)
• cool
• clammy skin
• dizziness (severe)
• drowsiness (severe)
• fast and irregular pulse
• fever
• hallucinations (seeing, hearing, or feeling things that are not there)
• headache (severe)
• high or low blood pressure
• muscle stiffness;

How to Store Isocarboxazid ?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date. Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.